Benzoyl Peroxide → HCID 54208606, compound

Participants

Reaction Steps

Ethyl 3-(4-fluorophenyl)-2-butenoate (548 g, 2.7 mol), N-bromosuccinimide (500 g, 2.8 mol) and benzoyl peroxide (6 g) are combined in carbon tetrachloride (4 L). The mixture is heated at reflux and irradiated with a UV lamp for 4 days. The mixture is then filtered and the filtrate evaporated, and the residue is dissolved in ether and washed five times with saturated aqueous sodium carbonate and once with brine. The ether layer is dried with magnesium sulfate and evaporated, to provide the title compound.

Provenance & Evidence