Hydrochloric Acid → HCID 13647226, compound

Participants

Reaction Steps

10 g of 2,3-Dichloro-7-methylbenzo[b]thiophene are dissolved in 200 ml ether and 28.8 ml of a 1.6M solution of butyllithium in hexane added dropwise at 0°. After one hour the mixture is poured into dilute aqueous HCl, the organic phase separated, washed, dried and concentrated on a rotary evaporator. The raw title product thus obtained is reacted directed further (B.p.=60°-62°/0.13 Pascal. 3-Chloro-4-methylbenzo[b]thiophene may be prepared analogously.

Provenance & Evidence