Ethanolamine → HCID 178435543, compound

HRID 64903Notes

Reaction equation

Br[CH:2]1[CH2:19][CH:18]([OH:20])[CH2:17][C:16]2[C:15]([OH:21])=[C:14]3[C:5]([C:6](=[O:29])[C:7]4[CH:8]=[CH:9][CH:10]([CH2:27][CH3:28])[C:11]5([O:26][CH2:25][CH2:24][O:23]5)[C:12]=4[C:13]3=[O:22])=[C:4]([OH:30])[C:3]1=2.[CH2:31]([CH2:33][NH2:34])[OH:32]>>[OH:32][CH2:31][CH2:33][NH:34][CH:2]1[CH2:19][CH:18]([OH:20])[CH2:17][C:16]2[C:15]([OH:21])=[C:14]3[C:5]([C:6](=[O:29])[C:7]4[CH:8]=[CH:9][CH:10]([CH2:27][CH3:28])[C:11]5([O:26][CH2:25][CH2:24][O:23]5)[C:12]=4[C:13]3=[O:22])=[C:4]([OH:30])[C:3]1=2

Participants

Reactant 2

HCID 700Ethanolamine

HCID 1784355427'-bromo-2'-ethyl-6',9',11'-trihydroxyspiro[1,3-dioxolane-2,1'-7,8,9,10-tetrahydro-2H-tetracene]-5',12'-dione

Product 1

HCID 178435543HCID 178435543, compound

Procedure

In the same manner as in Example 1 (2), 7-bromo-9-(1,1-ethylenedioxy)ethyl-6,9,11-trihydroxy-5,7,8,9,10,12-hexahydronaphthacene-5,12-dione (1.0 g) prepared in Example 1 (1) and ethanolamine (20 ml) were subjected to reaction to give 7-(2-hydroxyethyl)amino-9-(1,1-ethylenedioxy)ethyl-6,9,11-trihydroxy-5,7,8,9,10,12-hexahydronaphthacene-5,12-dione as orange crystals. M.P., 190° C. (decomp.).

Sources & evidence

ORD record: ord-d6b97973567947e8b1910c575aac1683
Source dataset: uspto-grants-1986_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04610986

Reaction notes

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