Methyl iodide → HCID 14555939, compound

HRID 649107Notes

Reaction equation

HRID 649107 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[C:7]([O:12][C:13]3[CH:26]=[CH:25][C:16]([O:17][CH:18]([CH3:24])[C:19]([O:21][CH2:22][CH3:23])=[O:20])=[CH:15][CH:14]=3)[CH:8]=[N:9]2)=[CH:4][CH:3]=1.[CH3:27][I:28]>ClCCl>[I-:28].[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[C:7]([O:12][C:13]3[CH:14]=[CH:15][C:16]([O:17][CH:18]([CH3:24])[C:19]([O:21][CH2:22][CH3:23])=[O:20])=[CH:25][CH:26]=3)[CH:8]=[N+:9]2[CH3:27])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 13079890HCID 13079890, compound

Product 1

HCID 14555939HCID 14555939, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Ethyl 2-{4-[(7-chloro-1-methylquinolinium-3-yl)oxy]phenoxy}propionate iodide salt (6) was prepared by reacting a mixture of ethyl 2-{4-[(7-chloroquinolin-3-yl)oxy]phenoxy}propionate (see Example 5) and methyl iodide in dichloromethane at ambient temperature for a period of four days. The product, a viscous oil, was characterized by its proton magnetic resonance spectrum. Pmr spectrum (CDCl3 ; δ in ppm): 9.8 (1H, d); 8.6 (2H, m); 8.3 (1H, d); 7.75 (1H, d of d); 7.1 (4H, d of d); 4.8 (4H, m); 4.15 (2H, q); 1.55 (3H, d); 1.25 (3H, t).

Sources & evidence

ORD record
ord-b93a53528d464dfcaf91926def571fcb
Source dataset
uspto-grants-1988_04
Patent number
US04738710

Reaction notes

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