HCID 178498220, compound → HCID 178464171, compound

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Reaction Steps

Compounds in accordance with the present invention are prepared from the starting materials 6-formyl-4,7,9-trihydroxy-1-phenazinecarboxylic acid, methyl ester or from 6-formyl-4,7,9-trihydroxy-8-methyl-1-phenazinecarboxylic acid, methyl ester. The former compound, 6-formyl-4,7,9-trihydroxy-1-phenazinecarboxylic acid, methyl ester, is known variously in the chemical literature as lomofungin or lomondomycin and is produced in isolable quantities from fermentation broth mixtures containing the microorganism Streptomyces lomondensis NRRL 3252 as detailed in U.S. Pat. No. 3,359,165.

Provenance & Evidence