HCID 54693282, compound → HCID 54717980, compound

Participants

Reaction Steps

A mixture consisting of 34.5 parts of N-(4-nitrophenyl)-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-quinoline-3-carboxamide (1:20), 0.3 parts of platinic oxide, and 330 parts of toluene is hydrogenated at 50° C. and at 5 atm. The catalyst is filtered off and the filtrate is evaporated to dryness in vacuo. The residue crystallizes to give N-(4-aminophenyl)-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-quinoline-3-carboxamide (1). M.p. 300° C.

Provenance & Evidence