Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 649201Generated: October 26, 2026

Quinoline → 2-Phenyl-1,2,3,4-tetrahydroquinoline

https://huagongshe.com/reaction/649201

Reaction equation

Participants

RoleNameHCIDCharge
ReactantQuinolineHCID 7047—
ReactantHCID 178419663HCID 178419663—
ReactantHCID 178506676HCID 178506676—
SolventDiethyl EtherHCID 3283—
Product2-Phenyl-1,2,3,4-tetrahydroquinolineHCID 10752915—

Reaction Steps

By the 3-step method of Preparation E, substituting 1M phenyllithium in ether for the benzylmagnesium bromide solution, quinoline (25 g, 0.194 mol) was converted to present title product, 22.4 g, as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04738972
Source datasetuspto-grants-1988_04
ORD IDord-14a187deddf0425e914ed4619b3b5fe1
Source noteuspto-grants-1988_04