HCID 10497335, compound → HCID 14155093, compound

HRID 649454Notes

Reaction equation

HRID 649454 reaction equation
[CH2:1]([S:8][C:9]1[N:23]=[C:12]2[N:13]=[C:14]([O:17][CH2:18][C:19](F)(F)F)[CH:15]=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C>[CH2:1]([S:8][C:9]1[N:23]=[C:12]2[N:13]=[C:14]([O:17][CH2:18][CH3:19])[CH:15]=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 10497335HCID 10497335, compound

Product 1

HCID 14155093HCID 14155093, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This material was prepared by heating 2-benzylthio-5-(2,2,2-trifluoroethoxy)-1,2,4-triazolo[1,5-a]pyrimidine in boiling ethanol. The hot mixture was filtered and the filtrate was concentrated. The crude product was recrystallized from isopropanol to yield the desired product as a solid, m.p. 115°-117° C. IR and 1HNMR spectra were in agreement with the assigned structure.

Workup

  1. customThis material was prepared
  2. filtrationThe hot mixture was filtered
  3. concentrationthe filtrate was concentrated
  4. customThe crude product was recrystallized from isopropanol

Sources & evidence

ORD record
ord-6cfce53d0e984c02a470f7a43cdfee28
Source dataset
uspto-grants-1988_04
Patent number
US04740233

Reaction notes

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