Acetyl chloride → 2-Acetoxymethyl-6-chloroaniline

HRID 649478Notes

Reaction equation

HRID 649478 reaction equation
[NH2:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5].[C:11](Cl)(=[O:13])[CH3:12]>>[C:11]([O:5][CH2:4][C:3]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:10])[C:2]=1[NH2:1])(=[O:13])[CH3:12]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 14155407(2-Amino-3-chlorophenyl)methanol

Product 1

HCID 141554092-Acetoxymethyl-6-chloroaniline

Procedure

This material was prepared from 2-amino-3-chlorobenzyl alcohol and acetyl chloride by the general procedure outlined in Example 82. The product was isolated as an amber oil and was characterized by IR and 'H NMR spectroscopy and combustion analysis.

Workup

  1. customThe product was isolated as an amber oil

Sources & evidence

ORD record
ord-52c7c633e027477e81f00e1cb8b38088
Source dataset
uspto-grants-1988_04
Patent number
US04740233

Reaction notes

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