1,3-Difluoro-2-nitrobenzene → 2-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzene

HRID 649485Notes

Reaction equation

HRID 649485 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[N+:9]([O-:11])=[O:10].[Cl:12][C:13]1[CH:18]=[C:17]([C:19]([F:22])([F:21])[F:20])[CH:16]=[CH:15][C:14]=1[OH:23]>>[Cl:12][C:13]1[CH:18]=[C:17]([C:19]([F:20])([F:21])[F:22])[CH:16]=[CH:15][C:14]=1[O:23][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[N+:9]([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 879221,3-Difluoro-2-nitrobenzeneHCID 27366032-Chloro-4-(trifluoromethyl)phenol

Product 1

HCID 541374142-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzene

Procedure

This material was prepared in 47% yeild from 2,6-difluoronitrobenzene and 2-chloro-4-trifluoromethylphenol following the general procedure outlined in Example 88. The product was isolated as an oil which was characterized by IR and 1H NMR spectroscopy.

Workup

  1. customThe product was isolated as an oil which

Sources & evidence

ORD record
ord-f21a2cc26f0e469ab448ffba9521d53b
Source dataset
uspto-grants-1988_04
Patent number
US04740233

Reaction notes

Loading…