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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 649498생성일: 2026년 10월 25일

Anisole → HCID 178462746, 화합물

https://huagongshe.com/reaction/649498

반응식

참여 물질

역할이름HCID투입량
반응물AnisoleHCID 7519—
반응물1H-Benzimidazole, 5,6-dichloro-1-ethyl-2-methyl-HCID 76717—
반응물1-(2-Bromoethyl)pyrrolidine-2,5-dioneHCID 13561395—
용매Ethyl AcetateHCID 8857—
생성물HCID 178462746HCID 178462746—

반응 조건

온도130 °C

반응 단계

11.5 g of 5,6-dichloro-1-ethyl-2-methylbenzoimidazole and 20.6 g of N-(2-bromoethyl)succinimide were put into a 200-ml three-necked flask equipped with a stirrer and a reflux condenser and heated for 2 hours on an oil bath which has been heated to a temperature of 130° C. 10 ml of anisole was added to the mixture. The admixture was then allowed to stand for cooling. 50 ml of ethyl acetate was added to the admixture. The admixture was then refluxed for 30 minutes. After being allowed to cool to room temperature, the resulting crystal was filtered off, washed with acetone, and then dried at a temperature of 50° C. for 5 hours. Yield: 18.7 g (86%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04740455
출처 데이터셋uspto-grants-1988_04
ORD IDord-86e8fa36df7b4279be13c2ee187f9e9b
출처 메모uspto-grants-1988_04