Bromine → HCID 131715507, compound

HRID 649510Notes

Reaction equation

HRID 649510 reaction equation
[C:1]([N:4]1[C:18]2[C:19]3[CH:6]([CH2:7][C@@H:8]4[C:13]([C:14]=3[CH:15]=[CH:16][CH:17]=2)=[CH:12][C@H:11]([NH:20][C:21](=[O:27])[N:22]([CH2:25][CH3:26])[CH2:23][CH3:24])[CH2:10][N:9]4[CH3:28])[CH2:5]1)(=[O:3])[CH3:2].[Br:29]Br>C(O)(=O)C>[C:1]([N:4]1[C:18]2[C:19]3[C:6]([CH2:7][C@@H:8]4[C:13]([C:14]=3[C:15]([Br:29])=[CH:16][CH:17]=2)=[CH:12][C@H:11]([NH:20][C:21](=[O:27])[N:22]([CH2:25][CH3:26])[CH2:23][CH3:24])[CH2:10][N:9]4[CH3:28])=[CH:5]1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24408BromineHCID 131715508HCID 131715508, compound

Product 1

HCID 131715507HCID 131715507, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The compound is produced by reacting 3-(1-acetyl-9,10-didehydro-2,3-dihydro-6-methyl-8α-ergolinyl)-1,1-diethylurea with elemental bromine in 5% acetic acid, analogously to Example 6.

Workup

  1. customThe compound is produced

Sources & evidence

ORD record
ord-6c78fd0a96e042a1b298b45678a3f18e
Source dataset
uspto-grants-1988_04
Patent number
US04740509

Reaction notes

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