HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → HCID 20141774, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 8-Methyl-6-(2-methyl-1H-imidazol-1-yl)quinolin-2(1H)-one | HCID 14450300 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20141774 | HCID 20141774 | — |
Reaction Steps
A mixture of 6-(2-methylimidazol-1-yl)-8-methyl-2-(1H)-quinolone (0.24 g) and N-chlorosuccinimide (0.14 g) in dichloromethane (10 cm3) was stirred at room temperature for 2 hours. The mixture was then chromatographed directly on silica (Merck "MK 60.9385" [Trade Mark]) eluting with methanol:dichloromethane, 1:20 by volume. Combination and evaporation of the appropriate fractions afforded the title compound, m.p. 258°-61°, (0.18 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04740513 |
| Source dataset | uspto-grants-1988_04 |
| ORD ID | ord-65d431df001c47e1bb02711f3aea0093 |
| Source note | uspto-grants-1988_04 |