Sodium Hydroxide → HCID 21243312, compound

Participants

Reaction Steps

A solution of 3.84 g of 3-[4-(6-formyl-3-indolyl)butyl]-1,2,3,4,5,6-hexahydrobenzo[f]isoquinoline in 40 ml of THF is added dropwise to a stirred suspension of 0.57 g of lithium aluminium hydride in 20 ml of THF under N2. The mixture is then stirred at 20° for 1 hour, and decomposition is carried out with dilute sodium hydroxide solution and then with water, and the mixture is filtered and the usual working up is carried out, and 3-[4-(6-hydroxymethyl-3-indolyl)butyl]-1,2,3,4,5,6-hexahydrobenzo[f]isoquinoline is obtained.

Provenance & Evidence