Ammonia → HCID 13750864, compound

HRID 649655Notes

Reaction equation

HRID 649655 reaction equation
[N+:1]([C:4]1[C:9]([N+:10]([O-])=O)=[CH:8][C:7]([OH:13])=[C:6]([O:14][CH3:15])[CH:5]=1)([O-:3])=[O:2].C(N)=O.N>O>[NH2:10][C:9]1[C:4]([N+:1]([O-:3])=[O:2])=[CH:5][C:6]([O:14][CH3:15])=[C:7]([OH:13])[CH:8]=1

Participants

5

Reactant 3

HCID 222AmmoniaHCID 713FormamideHCID 184586Phenol, 2-methoxy-4,5-dinitro-

Product 1

HCID 13750864HCID 13750864, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
95 °C

Procedure

A mixture consisting of 0.15 mol (32.1 g) of 4,5-dinitro-2-methoxyphenol, prepared in Example 2, 150 ml of formamide and 200 ml of 28% strength ammonia solution in water is heated to 95° C. for 8 hours in an autoclave. After the mixture is cooled, the expected product crystallizes. It is dissolved in the minimum quantity of dimethylformamide, and is then precipitated by adding water. It melts at 208° C.

Workup

  1. temperatureAfter the mixture is cooled
  2. customthe expected product crystallizes
  3. dissolutionIt is dissolved in the minimum quantity of dimethylformamide
  4. customis then precipitated
  5. additionby adding water

Sources & evidence

ORD record
ord-d3fbdc6170e54cfdb00d3d414659ae66
Source dataset
uspto-grants-1988_04
Patent number
US04740622

Reaction notes

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