Propylene → 2-Fluoro-6-isopropylaniline

HRID 649661Notes

Reaction equation

HRID 649661 reaction equation
[CH2:1]=[CH:2][CH3:3].[F:4][C:5]1[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=1[NH2:7]>>[F:4][C:5]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:2]([CH3:3])[CH3:1])[C:6]=1[NH2:7]

Participants

3

Reactant 2

HCID 8252Propylene2×HCID 95842-Fluoroaniline2×

Product 1

HCID 150147682-Fluoro-6-isopropylaniline

Procedure

2-fluoro-6-isopropyl aniline was prepared by the method of Example 2 using an H-Y zeolite catalyst for the condensation of 2-aniline and propylene. In this reaction 2-fluoroaniline and propylene were fed to a reactor in a 1:5 mole ratio and LHSV of 0.25 based on 2-fluoroaniline. The reaction was conducted at 255° C. and 879 psig. The effluent product stream was analyzed by gas chromatography. Conversion of 2-fluoroaniline was 71.2%.

Workup

  1. customwere fed to a reactor in a 1
  2. customwas conducted at 255° C.

Sources & evidence

ORD record
ord-d89cdea7afc641629ad73de353885a55
Source dataset
uspto-grants-1988_04
Patent number
US04740620

Reaction notes

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