HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)-2-methylpropan-1-ol → 1-(4-Fluorophenyl)-2-methylpropan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)-2-methylpropan-1-ol | HCID 10419564 | — |
| Reactant | Jones' reagent | HCID 131709961 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-(4-Fluorophenyl)-2-methylpropan-1-one | HCID 2782829 | — |
Reaction Steps
To a solution of 1-(4-Fluoro-phenyl)-2-methyl-propan-1-ol (1.6 g) in acetone (10 mL) at 0° C. is added Jones reagent (20 mL) with stirring. After 10 minutes excess Jones reagent is destroyed by addition of isopropyl alcohol. Diethyl ether is added followed by anhydrous magnesium and the mixture is filtered and evaporated to give the product, a yellow oil (1.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06271236B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-d4c80c07dc0849bea812fad49bcaf1b8 |
| Source note | uspto-grants-2001_08 |