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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 649896Generated: October 30, 2026

Ethyl 2-amino-1-benzothiophene-3-carboxylate → Ethyl 2-(5-bromo-2-nitroanilino)benzo[b]thiophene-3-carboxylate

https://huagongshe.com/reaction/649896

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-amino-1-benzothiophene-3-carboxylateHCID 699464—
Reactant2,4-Dibromo-1-nitrobenzeneHCID 12315646—
SolventDimethyl SulfoxideHCID 679—
ProductEthyl 2-(5-bromo-2-nitroanilino)benzo[b]thiophene-3-carboxylateHCID 18422260—

Reaction Steps

In the same manner as in Starting Material Synthesis Example 4 and using ethyl 2-aminobenzo[b]thiophene-3-carboxylate, 2,4-dibromonitrobenzene and dimethyl sulfoxide, ethyl 2-(5-bromo-2-nitroanilino)benzo[b]thiophene-3-carboxylate is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06271225B1
Source datasetuspto-grants-2001_08
ORD IDord-a148f2b3005c4536a30682d07963aad6
Source noteuspto-grants-2001_08