HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-3-nitrotoluene → Ethyl 2-(4-methyl-2-nitroanilino)benzo[b]thiophene-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-3-nitrotoluene | HCID 136287 | — |
| Reactant | Ethyl 2-amino-1-benzothiophene-3-carboxylate | HCID 699464 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Ethyl 2-(4-methyl-2-nitroanilino)benzo[b]thiophene-3-carboxylate | HCID 18422341 | 100.9% |
Reaction Steps
In the same manner as in Starting Material Synthesis Example 4 and using ethyl 2-aminobenzo[b]thiophene-3-carboxlate (4.0 g), 4-fluoro-3-nitrotoluene (3.3 g) and dimethyl sulfoxide (55 ml), ethyl 2-(4-methyl-2-nitroanilino)benzo[b]thiophene-3-carboxylate (6.5 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06271225B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-033e2e78be75422387245c0cc595c7ad |
| Source note | uspto-grants-2001_08 |