1-Fluoro-2-nitrobenzene → HCID 18422272, compound

HRID 649905Notes

Reaction equation

HRID 649905 reaction equation
[NH2:1][C:2]1[S:6][C:5]2[CH:7]=[C:8]([O:11][CH3:12])[CH:9]=[CH:10][C:4]=2[C:3]=1[C:13]([O:15][CH2:16][CH3:17])=[O:14].F[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[N+:25]([O-:27])=[O:26]>CS(C)=O>[CH3:12][O:11][C:8]1[CH:9]=[CH:10][C:4]2[C:3]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[C:2]([NH:1][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=3[N+:25]([O-:27])=[O:26])[S:6][C:5]=2[CH:7]=1

Participants

4

Reactant 2

HCID 738951-Fluoro-2-nitrobenzeneHCID 18422175HCID 18422175, compound

Product 1

HCID 18422272HCID 18422272, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

In the same manner as in Starting Material Synthesis Example 4 and using ethyl 2-amino-6-methoxybenzo[b]thiophene-3-carboxylate, 2-fluoronitrobenzene and dimethyl sulfoxide, ethyl 6-methoxy-2-(2-nitroanilino)benzo[b]thiophene-3-carboxylate is obtained.

Workup

  1. customMaterial Synthesis Example 4

Sources & evidence

ORD record
ord-c07a3d53c41c416d905f1003d0677b33
Source dataset
uspto-grants-2001_08
Patent number
US06271225B1

Reaction notes

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