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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 649934Generated: October 30, 2026

Anisole → HCID 135816413, compound

https://huagongshe.com/reaction/649934

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnisoleHCID 7519—
Reactant1-MethylpiperazineHCID 53167—
ReactantHCID 18422285HCID 18422285—
CatalystTitanium TetrachlorideHCID 24193—
ProductHCID 135816413HCID 135816413—

Reaction Steps

In the same manner as in Example 1 and using ethyl 2-(2-amino-4-fluoroanilino)benzo[b]thiophene-3-carboxylate, 1-methylpiperazine, anisole and titanium tetrachloride, 9-fluoro-12-(4-methylpiperazin-1-yl)-6H-[1]benzothieno[2,3-b][1,5]benzdiazepine is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06271225B1
Source datasetuspto-grants-2001_08
ORD IDord-674db8ee9d8842feabe808476f921d31
Source noteuspto-grants-2001_08