HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 650010Generated: October 28, 2026
2-isopropenylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one → 2-isopropylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one
https://huagongshe.com/reaction/650010
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-isopropenylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one | HCID 18422274 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-isopropylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one | HCID 18422230 | 76.3% |
Reaction Steps
2-Isopropenylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one (780 mg) was suspended in dioxane (40 ml) and 10% palladium-activated charcoal (100 mg) was added. Hydrogen was sealed in and the mixture was stirred at 40° C., 50 atm for 7.5 hours. The catalyst was filtered off and the solvent was evaporated under reduced pressure to give 2-isopropylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one (600 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06271225B1 |
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| Source dataset | uspto-grants-2001_08 |
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| ORD ID | ord-7838093cb1f74c4ca2f6d2eabd51f4b0 |
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| Source note | uspto-grants-2001_08 |
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