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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 650014Generated: October 30, 2026

N,N-Dimethylaniline → HCID 18422256, compound

https://huagongshe.com/reaction/650014

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-DimethylanilineHCID 949—
ReactantPhosphorus oxychlorideHCID 24813—
Reactant1-MethylpiperazineHCID 53167—
Reactant8-fluoro-2-methylthieno[2,3-b][1,5]benzoxazepin-4(5H)-oneHCID 18422316—
ProductHCID 18422256HCID 18422256—

Reaction Steps

In the same manner as in Example 125 and using 8-fluoro-2-methylthieno[2,3-b][1,5]benzoxazepin-4(5H)-one, phosphorus oxychloride, N,N-dimethylaniline and 1-methylpiperazine, 8-fluoro-2-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-b][1,5]benzoxazepine is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06271225B1
Source datasetuspto-grants-2001_08
ORD IDord-beb76070cad34ff8a9e859bb820a0f9d
Source noteuspto-grants-2001_08