HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 650105Generated: October 30, 2026
Benzyl isocyanate → HCID 21714410, compound
https://huagongshe.com/reaction/650105
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzyl isocyanate | HCID 76639 | — |
| Reactant | 2-Amino-6-(trifluoromethyl)phenol | HCID 22272746 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21714410 | HCID 21714410 | 80.6% |
Reaction Steps
To a solution of benzylisocyanate (74.56 mg, 0.56 mmol) in DMF (1.0 ml), 2-hydroxy-3-trifluoromethylaniline (100 mg, 0.56 mmol) was added. The reaction mixture was stirred at 80° C. for 16 hours. Chromatography of the resulting liquid on silica gel gave desired product (140 mg, 80%). EI-MS m/z 311.1 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06271261B1 |
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| Source dataset | uspto-grants-2001_08 |
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| ORD ID | ord-c8ed9ed6e5624c16a62692ec914137eb |
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| Source note | uspto-grants-2001_08 |
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