HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6R-Tetrahydrofolic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tetrahydrofolic acid | HCID 135444742 | — |
| Product | 6R-Tetrahydrofolic acid | HCID 135415876 | — |
Reaction Steps
One half of the mother liquor is precipitated with 1.1 g of ethanol, giving enriched amorphous (6R) tetrahydrofolic acid with a chemical content of 63.3% and a (6R) percentage of 75.9, while in the other half of the mother liquor the pH is rapidly brought to 3.5 using 6.3 g of hydrochloric acid, resulting in enriched, amorphous (6R)-tetrahydrofolic acid with a chemical content of 64.8% and a (6R) percentage of 75.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06271374B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-ba13fb71265e44a3a2e367ba88d0b4bf |
| Source note | uspto-grants-2001_08 |