Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 650255Generated: October 26, 2026

Isobutylene oxide → 3-Butyl-5,5-dimethyl-2-propyl-1,3-oxazolidine

https://huagongshe.com/reaction/650255

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsobutylene oxideHCID 11208—
ReactantN-ButylidenebutylamineHCID 94840—
SolventTetrahydrofuranHCID 8028—
Product3-Butyl-5,5-dimethyl-2-propyl-1,3-oxazolidineHCID 1019810453%

Reaction Steps

A mixture of 1 mmol of N-butylidenebutylamine, 2 mmol of 1,2-epoxy-2-methylpropane, 0.05 mmol of Cp*2Sm(THF)2, and 1 ml of tetrahydrofuran was stirred at room temperature for 5 hours. Products in a reaction mixture were isolated through column chromatography to yield 3-butyl-5,5-dimethyl-2-propyl-1,3-oxazolidine in yield of 53%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06271387B1
Source datasetuspto-grants-2001_08
ORD IDord-bc4876b4c7e448fa93ee94167222db60
Source noteuspto-grants-2001_08