HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxydecanoic Acid → n-((5s)-3-(4-(1-{2-Hydroxy-decanoyl}-1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxydecanoic Acid | HCID 21488 | — |
| Reactant | N-((5S)-3-(4-(1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide | HCID 20638827 | — |
| Product | n-((5s)-3-(4-(1-{2-Hydroxy-decanoyl}-1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide | HCID 57210494 | — |
Reaction Steps
Using an analogous procedure to that described in Example 20, the TFA salt of Example 2 was reacted with 2-hydroxydecanoic acid in place of N-acetylglycine, to give the title compound. Yield=252 mg, 65%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06271383B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-31fe6e7f88f04713afe76ddff3a4cf39 |
| Source note | uspto-grants-2001_08 |