HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indene → 2-[3,5-Bis(trifluoromethyl)phenyl]-1H-indene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indene | HCID 7219 | — |
| Reactant | 1-Iodo-3,5-bis(trifluoromethyl)benzene | HCID 630970 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 2-[3,5-Bis(trifluoromethyl)phenyl]-1H-indene | HCID 12010625 | — |
Reaction Steps
20 ml of triethylamine, 2.2 g (20 mmole) of indene, 6.8 g (20 mmole) of 1-iodo-3,5-bis(trifluoromethyl)-benzene and 0.134 g (0.6 mmole) and 0.134 g (0.6 mmole) of Pd(OAc)2 were stirred under relux for 12 h. After it all triethylamine was removed under reduced pressure. The residue was treated with the mixture 50 ml of water and 50 ml of diethyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06271411B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-f1e9133ef0e54f7295b0c949d591a90e |
| Source note | uspto-grants-2001_08 |