HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybiphenyl → 4-Phenylbenzene-1-thiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybiphenyl | HCID 7103 | — |
| Reactant | Dimethylthiocarbamoyl chloride | HCID 27871 | — |
| Product | 4-Phenylbenzene-1-thiol | HCID 2760414 | 39% |
Reaction Steps
The reaction of p-hydroxybiphenyl with dimethylthiocarbamoyl chloride followed by Newman-Kwart rearrangement and finally hydrolysis (see J. Het. Chem. 15, 281 (1978) and WO 96/25 936) affords 4-mercaptobiphenyl only in a yield of 39%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06271415B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-449312bae85e473ea90313a75110cecd |
| Source note | uspto-grants-2001_08 |