HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 15542228, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 22941804 | HCID 22941804 | — |
| Product | HCID 15542228 | HCID 15542228 | 64.8% |
Reaction Steps
Under the conditions of Example 8, 500 mg of 3-hydroxy-7α-{5-[(2S)-2-(4,4,5,5,5-pentafluoropentylthiomethyl)-pyrrolidin-1-yl]-pentyl}-estra-1,3,5(10)-trien-17-one is reduced with 100 mg of sodium borohydride. 325 mg of the title compound is obtained as oil. [α]D22=−8.7° (c=0.510 in methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06271403B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-e573ec2364de44da89822401d8e1f95c |
| Source note | uspto-grants-2001_08 |