HuagongsheHuagongshe Chemistry Print Report · For research reference only
2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-methyl- → 2-methylamino-5 chloro-N-benzyloxylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-1-methyl- | HCID 26724 | — |
| Reactant | Benzyloxyamine hydrochloride | HCID 102312 | — |
| Product | 2-methylamino-5 chloro-N-benzyloxylbenzamide | HCID 21712116 | 50.6% |
Reaction Steps
In the same manner as Example 35(a), O-benzylhydroxylamine hydrochloride (1.92 g, 12 mmol) reacted with N-methyl-5-chloro-isatoic anhydride (2.13 g, 10 mmol) to give 2-methylamino-5 chloro-N-benzyloxylbenzamide as a white solid (1.47 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06274383B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-a526a6848e6145489fb6fd207148bb55 |
| Source note | uspto-grants-2001_08 |