Carbon Disulfide → 2-Thenyl (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline-2-carbodithioate

Participants

Reaction Steps

In the same manner as described in Example 8 by using (3S)-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline (2.02 g), 2N NaOH (10 ml), CS2 (1.5 g), 2-Thenyl chloride (2.65 g), and 80% ethanol (50 ml), there is prepared the title compound (1.86 g, 50%) as white powder, [α]D20 +108.4° (c=1.0, methanol). NMR (CDCl3, δ): 4.84 (s, 2H, CSSCH2 -- ##STR8## Mass m/e: 374 (M+), 244 (M+ -- ##STR9##

Provenance & Evidence