Methyl iodide → Methyl (1RS, 3RS)-cis-1-butyl-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline-2-carbodithioate

Participants

Reaction Steps

In the same manner as described in Example 13 by using (1RS, 3RS)-cis-1-butyl-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline (1.05 g), triethylamine (0.53 g), CS2 (0.50 g), methyl iodide (0.95 g) and dimethylsulfoxide (8 ml), there is prepared the title compound (0.85 g, 61%) as white powder. NMR (CDCl3, δ): 0.96 (t, J=7.0 Hz, 3H, C1 --(CH2)3CH3), 2.72 (s, 3H, CSSCH3), Mass m/e: 348 (M+), 300 (M+ --CH3SH).

Provenance & Evidence