Thionyl Chloride → HCID 21712905, compound

Participants

Reaction Steps

Thionyl chloride (200 ml) in dry n-hexane (400 ml) was stirred at ambient temperature and 4,4-difluorobut-3-enyl-sulfinic acid sodium salt ( 44 g) was added in portions. On complete addition the mixture was heated to reflux under nitrogen for 4.5 hours, cooled to ambient temperature then filtered. The filtrate was evaporated under reduced pressure to give a liquid which was distilled and the fraction collected at bp 50-60° C. at 0.1 mm Hg to yield

Provenance & Evidence