Carbon Disulfide → 4-Nitrobenzyl (3RS)-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline-2-carbodithioate

Participants

Reaction Steps

In the same manner as described in Example 29 by using (3RS)-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline (1.01 g), triethylamine (0.77 ml), CS2 (0.33 ml), 4-nitrobenzyl chloride (1.08 g) and 80% methanol (20 ml), there is prepared the title compound (1.47 g, 71%) as pale yellow needles, m.p. 193°-194° C. (recrystallized from aqueous methanol), NMR (DMSO-d6, δ): 4.79 (s, 2H, ##STR14## Mass m/e: 244 (M+ -- ##STR15##

Provenance & Evidence