Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 650775Generated: October 29, 2026

HCID 44211033, compound → HCID 44211034, compound

https://huagongshe.com/reaction/650775

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 44211033HCID 44211033—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 44211034HCID 4421103484.4%

Reaction Steps

To a solution of (1RS, 2SR, 3SR)-3-[2-[(E)-2-carboxy-ethen-1-yl]-4-methoxyphenyl]-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid (43 mg, 0.08 mmol) in ethanol (5 mL) was added 10% palladium on activated carbon (40 mg). The resulting suspension was stirred overnight under an atmosphere of hydrogen then filtered through a pad of celite. The filtrate was concentrated under reduced pressure to afford the title compound (35 mg, 82%) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06274737B1
Source datasetuspto-grants-2001_08
ORD IDord-ab394d9ce82144c1b0106f3a2ebe4498
Source noteuspto-grants-2001_08