HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 86741018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Carbon Disulfide | HCID 6348 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | (1RS, 3SR)-trans-1-propyl-3-hydroxymethyl-1,2,3,4-tetrahydro-beta-carboline | HCID 86741019 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 86741018 | HCID 86741018 | 44.6% |
Reaction Steps
In the same manner as described in Example 39 by using (1RS, 3SR)-trans-1-propyl-3-hydroxymethyl-1,2,3,4-tetrahydro-β-carboline (1.18 g), triethylamine (0.98 g), CS2 (0.74 g), methyl iodide (1.37 g) and dimethylsulfoxide (23 ml), there is prepared the title compound (720 mg, 44%) as white powder, NMR (CDCl3, δ): 2.70 (s, 3H, CSSCH3); Mass m/e: 334 (M+), 286 (M+ --CH3SH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04612317 |
| Source dataset | uspto-grants-1986_09 |
| ORD ID | ord-5a2c4ade8d18430aba0b0f4078cc5221 |
| Source note | uspto-grants-1986_09 |