HRID650787

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2734893

Methyl L-threoninate hydrochloride

C5H12ClNO3

$结构：CCC=CCC=CCC=CCC=CCC=CC/C=C\CCC(=O)O$

HCID73013253

未命名化合物

$结构：CCCCCC=CCC=CCC=CC/C=C\CCCC(=O)N[C@@H](COP(=O)(O)O)C(=O)O$

HCID86583929

未命名化合物

PRODUCTS

生成物

$结构：CCC=CCC=CCC=CCC=CCC=CC/C=C\CCC(=O)N[C@H](C(=O)O)[C@@H](C)OP(=O)(O)O$

HCID86583932

未命名化合物

PROCEDURE

实验过程

This compound was prepared as described above for (6) using 0.5 nmmol (164 mg) of cis-4,7,10,13,16,19-docosahexaenoic acid and 1 mmol (170 mg) of L-threonine methyl ester hydrochloride; yield 109 mg, (43%); Rf 0.05-0.10 (system B); 1H-NMR (CD3SOCD3, 200 MHz) δ0.9-1.0 (t, 3H, ω-CH3); 1.2-1.4 (3H, d, CH3CHOP); 2.0-2.1 (t, 2H, CH2CO); 2.2-2.4 (m, 4H, 2CH2CH═CH); 2.7-2.9 (br s, 10H, 5HC═CHCH2CH═CH); 4.1-4.3 (m, 2H, 2CH); 5.2-5.4 (br s, 12H, 6HC═CH); 8.2-8.4 (m, 3H, NH and 2POH)

WORKUP

后处理

customThis compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1b704c20f5a24b9cb585cda654d75e94
来源数据集: uspto-grants-2001_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06274747B1
来源说明: uspto-grants-2001_08

反应 SMILES

[C:1]([NH:22][C@H:23]([C:30]([OH:32])=[O:31])[CH2:24][O:25][P:26]([OH:29])([OH:28])=[O:27])(=[O:21])[CH2:2][CH2:3][CH2:4]/[CH:5]=[CH:6]\[CH2:7][CH:8]=[CH:9][CH2:10][CH:11]=[CH:12][CH2:13][CH:14]=[CH:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[C:33](O)(=O)[CH2:34]C/C=C\CC=CCC=CCC=CCC=CCC=CCC.Cl.[CH3:58]OC(=O)[C@H]([C@@H](C)O)N>>[C:1]([NH:22][C@H:23]([C:30]([OH:32])=[O:31])[C@@H:24]([CH3:58])[O:25][P:26]([OH:29])([OH:28])=[O:27])(=[O:21])[CH2:2][CH2:3]/[CH:4]=[CH:5]\[CH2:6][CH:7]=[CH:8][CH2:9][CH:10]=[CH:11][CH2:12][CH:13]=[CH:14][CH2:15][CH:16]=[CH:17][CH2:18][CH:19]=[CH:20][CH2:33][CH3:34]