N-(cis-5,8,11,14-Eicosatetraenoyl)-O-Phospho-L-Tyrosine → N-(cis-5,8,11,14,17-Eicosapentaenoyl)-O-Phospho-L-Tyrosine

関与物質

反応手順

This compound was prepared as described above for (8), using 0.5 mmol (151 mg) of cis-5,8,11,14,17-eicosapentaenoic acid; yield 65 mg, (24%); Rf 0.05-0.10 (system B); 1H-NMR (CD3SOCD3, 200 MHz) δ0.9-1.0 (t, 3H, ω-CH3); 1.5-1.6 (t, 2H, CH2); 2.0-2.2 (m, 6H, CH2CO and 2CH2CH═CH); 2.7-3.0 (m, 10H, 4HC═CH—CH2—CH═CH and CH2Ar); 4.3-4.4 (m, 1H, NHCHCO); 5.2-5.4 (br s, 10H, 5HC═CH); 7.1 (s, 4H, Ar); 8.2-8.4 (m, 3H, NH and 2POH)

情報源と証拠