反应详情

To a solution of 300 mg of 5-benzoyl-6-methylthio-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid in 5 ml of methanol is added 1 molar equivalent of sodium hydroxide, in the form of a 0.1N solution. The solvent is evaporated in vacuo and the residue is taken up in 2 ml of methanol, followed by precipitation with ether, to yield crude sodium 5-benzoyl-6-methylthio-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylate.

1. customThe solvent is evaporated in vacuo
2. customfollowed by precipitation with ether