Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosgene → N-Propyl-N-(tetrahydrofuran-3-yl)carbamoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosgene | HCID 6371 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | N-Propyl-N-(tetrahydrofuran-3-yl)amine | HCID 21709909 | — |
| 생성물 | N-Propyl-N-(tetrahydrofuran-3-yl)carbamoyl chloride | HCID 21709911 | — |
반응 단계
94 g (0.95 mol) of phosgene, 41 g (0.32 mol) of N-propyl-N-(tetrahydrofuran-3-yl)amine and 32 g (0.32 mol) of triethylamine were reacted by the method of the process described in Intermediate 1.2. Yield 54 g. 1H NMR (270 MHz, in CDCl3): δ=0.92 (t, 3H), 1.70 (sext., 2H), 2.02 (s, 1H), 2.30 (s, 1H), 3.20-3.40 (m, 2H), 3.65-3.85 (m, 3H), 4.05 (m, 1H), 4.50-4.70 and 4.85-5.05 (2 m, together 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06277790B1 |
| 출처 데이터셋 | uspto-grants-2001_08 |
| ORD ID | ord-5964de82f91b47fe904d835b244817db |
| 출처 메모 | uspto-grants-2001_08 |