MAGNESIUM SILICATE (synthetic) → HCID 21706141, compound

Participants

Reaction Steps

To a stirred suspension of 1.85 g (7.69 mmol) of carbinol from Step E in 50 mL CH2Cl2 was added 270.1 mg (0.769 mmol) of tetrapropylammonium perruthenate. After stirring for 5 minutes, 1.35 g (11.5 mmol) of solid N-methyl-morpholine-N-oxide was added all at once, and the resulting mixture stirred further for 5 minutes. The dark solution was passed over a column of florisil eluted with CH2Cl2-EtOAc (10:1) to give 1.42 g of the title aldehyde as a yellow solid.

Provenance & Evidence