HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[4-(4,5-Dihydrooxazol-2-yl)phenyl]piperazine → 2-[3-(2-Aminoethyl)-1h-indol-5-yloxy]-1-{4-[4-(4,5-dihydrooxazol-2-yl)phenyl]piperazin-1-yl}ethanone fumarate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[4-(4,5-Dihydrooxazol-2-yl)phenyl]piperazine | HCID 18504834 | — |
| Reactant | 1-[4-(5-Phenyl-[1,3,4]oxadiazol-2-yl)phenyl]piperazine | HCID 18504839 | — |
| Reactant | SerBOC | HCID 57270561 | — |
| Product | 2-[3-(2-Aminoethyl)-1h-indol-5-yloxy]-1-{4-[4-(4,5-dihydrooxazol-2-yl)phenyl]piperazin-1-yl}ethanone fumarate | HCID 18504844 | — |
Reaction Steps
Compound 5 is prepared from intermediate 5B (576 mg; 2.48 mmol) and SerBOC acid (694 mg; 2.07 mmol) according to the procedure described for the preparation of Example 1 from 1C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06277853B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-449049fcc16a4ea78a2a5892e7842b26 |
| Source note | uspto-grants-2001_08 |