HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3-Chloro-4-(propan-2-yloxy)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 3-chloro-4-isopropoxybenzoate | HCID 22597811 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Chloro-4-(propan-2-yloxy)benzoic acid | HCID 22597728 | 83.1% |
Reaction Steps
Methyl 3-chloro-4-isopropoxybenzoate (5.5 g, 24.1 mmol) was hydrolysed using 1M NaOH (36 ml) in methanol (80 ml). Extraction and work-up with ethyl acetate gave the title compound (4.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06277861B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-03d26cef444145b4b90392f768129125 |
| Source note | uspto-grants-2001_08 |