Bromine → HCID 22597763, compound

HRID 650959Notes

Reaction equation

HRID 650959 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([CH:12]([CH3:14])[CH3:13])[CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].[Br:15]Br>C(Cl)(Cl)Cl>[Br:15][C:9]1[C:10]([CH:12]([CH3:14])[CH3:13])=[CH:11][C:3]([O:2][CH3:1])=[C:4]([CH:8]=1)[C:5]([OH:7])=[O:6]

Participants

4

Reactant 2

HCID 24408BromineHCID 126137372-Methoxy-4-(propan-2-yl)benzoic acid

Product 1

HCID 22597763HCID 22597763, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

To a solution of 2-methoxy-4-iso-propyl benzoic acid (7.0 g, 36.0 mmol) in chloroform (100 ml) was added bromine (1.86 ml) in chloroform (20 ml) dropwise. The reaction was stirred at room temperature overnight Evaporation in vacuo afforded an oil (9.27 g). m/z (CI): 275, 273 (MH+; 70%).

Workup

  1. customEvaporation in vacuo

Sources & evidence

ORD record
ord-dac6b3c6de964a00a9ea2a0be5deba9f
Source dataset
uspto-grants-2001_08
Patent number
US06277861B1

Reaction notes

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