5-Amino-1,2-dimethyl-1,2,3,4-tetrahydroisoquinoline → (+/-) N-(1,2-Dimethyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-4-ethoxy-2-methoxybenzamide, hydrochloride

Participants

Reaction Steps

The title compound was prepared in a similar fashion to Example 1 from 5-amino-1,2-dimethyl-1,2,3,4-tetrahydroisoquinoline and 5-chloro-4-ethoxy-2-methoxybenzoic acid. The crude product was recrystallised from methanol and ethyl acetate to afford a pale brown solid (319 mg).

Provenance & Evidence