HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-[2-(dimethylamino)ethoxy]benzoate → 2-(2-Dimethylamino-ethoxy)-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-[2-(dimethylamino)ethoxy]benzoate | HCID 15390903 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 2-(2-Dimethylamino-ethoxy)-benzoic acid | HCID 6484659 | — |
Reaction Steps
4.4 g of methyl 2-[2-(N,N-dimethylamino)ethyl]oxy-benzoate are heated in the microwave for 15 minutes at 300 W with 30 ml of 5N hydrochloric acid. The mixture is extracted with ethyl acetate, the aqueous phase is concentrated by evaporation and recrystallised from acetonitrile/ether. Yield: 4.2 g (86% of theory).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06277872B1 |
| Source dataset | uspto-grants-2001_08 |
| ORD ID | ord-255bebdb22d24c1199dd173a72b94a50 |
| Source note | uspto-grants-2001_08 |