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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 651012Generated: October 27, 2026

2-Bromo-3'-chloroacetophenone → 3-Amino-6-chloro-2-(3-chlorobenzoyl)-1-(ethoxycarbonyl)indole

https://huagongshe.com/reaction/651012

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-3'-chloroacetophenoneHCID 38738—
Reactant4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrileHCID 18367888—
Product3-Amino-6-chloro-2-(3-chlorobenzoyl)-1-(ethoxycarbonyl)indoleHCID 18367868—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-[(ethoxycarbonyl)amino]benzonitrile (Example 1, step 1) and 2-bromo-3′-chloroacetophenone (M. Kihara, M. Kashimoto, and Y. Kobayashi, Tetrahedron, 1992, 48, 67-78.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06277878B1
Source datasetuspto-grants-2001_08
ORD IDord-f467cf3a30e347d8bfaa8ebea022dc0b
Source noteuspto-grants-2001_08