1-(4-Chloro-pyridin-2-yl)-ethanone → 1-(4-Methoxy-pyridin-2-yl)-ethanone
Reaction equation
[CH3:1][O:2]C1C=CN=C(C#N)C=1.[C:11]([C:14]1[CH:19]=[C:18](Cl)[CH:17]=[CH:16][N:15]=1)(=[O:13])[CH3:12]>>[C:11]([C:14]1[CH:19]=[C:18]([O:2][CH3:1])[CH:17]=[CH:16][N:15]=1)(=[O:13])[CH3:12]Participants
3
Procedure
The title compound was prepared from 4-methoxy-2-piridinecarbonitrile by using the procedure described for the preparation of 2-acetyl4-chloropyridine.
Sources & evidence
- ORD record
- ord-9cf9e8ee8e51424d9f2fc26571e90997
- Source dataset
- uspto-grants-2001_08
- Patent number
- US06277878B1
Reaction notes
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