1-Propanesulfonyl chloride → N-(2-Benzoyl-6-Chloro-1H-Indol-3-Yl)Propanesulfonamide

HRID 651023Notes

Reaction equation

HRID 651023 reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[N:4](C(OCC)=O)[C:3]=1[C:17](=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[CH2:25]([S:28](Cl)(=[O:30])=[O:29])[CH2:26][CH3:27]>>[C:17]([C:3]1[NH:4][C:5]2[C:10]([C:2]=1[NH:1][S:28]([CH2:25][CH2:26][CH3:27])(=[O:30])=[O:29])=[CH:9][CH:8]=[C:7]([Cl:11])[CH:6]=2)(=[O:24])[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 662791-Propanesulfonyl chlorideHCID 183678333-Amino-2-benzoyl-6-chloro-1-(ethoxycarbonyl)indole

Product 1

HCID 9799849N-(2-Benzoyl-6-Chloro-1H-Indol-3-Yl)Propanesulfonamide

Procedure

The title compound was prepared according to the procedure described in Example 33 from ethyl 3-amino2-benzoyl-6-chloro-1H-indole-1-carboxylate (Example 1, step 2) and 1 -propanesulfonyl chloride.

Sources & evidence

ORD record
ord-1f746282397d4923b7371804208de561
Source dataset
uspto-grants-2001_08
Patent number
US06277878B1

Reaction notes

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